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transfusion, particularly when an urgent clinical decision is required. It summarizes key information from a more extensive module of learning material: The clinical Use of Blood Manual.The handbook introduces the principles of the appropriate use of blood and blood products and outlines the characteristics and indications for use of intravenous replacement fluids, whole blood, blood components and plasma derivatives. It provides a detailed guide to clinical transfusion procedures and the recognition and management of transfusion reactions. Comprehensive guidance is given on transfusion and alternatives to transfusion in the areas of general medicine, obstetrics, paediatrics and neonatology, surgery and anaesthesia, trauma and acute surgery, and burns. Key points, tables and algorithms are highlighted for easy reference and a comprehensive index is included.